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About Sugammadex Sodium API

Product
  • Therapeutic CategoryCentral Nervous System (CNS)

  • CAS Number

    343306-79-6

  • API Technology

    Synthetic

  • Dose Form

    Injectable

  • Dr Reddy's Development Status

    Available

  • Available Regulatory Filing

    USDMF, Brazil DMF, EUDMF, Canada DMF, Japan DMF, Korea DMF, Russia DMF, China DMF

Mechanism of Action

BRIDION is a modified gamma cyclodextrin. It forms a complex with the neuromuscular blocking agents rocuronium and vecuronium, and it reduces the amount of neuromuscular blocking agent available to bind to nicotinic cholinergic receptors in the neuromuscular junction. This results in the reversal of neuromuscular blockade induced by rocuronium and vecuronium.

Indication

BRIDION is indicated for the reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide in adults undergoing surgery.

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Related Resources

Managing the Product Life Cycle: Naproxen API and formulations

Managing the Product Life Cycle: Naproxen API and formulations

Naproxen is a non-steroidal anti-inflammatory drug (NSAID) used in treating pain, menstrual cramps, and inflammatory diseases such as rheumatoid arthritis and fever.

Sustainable Supply chain

SustainableSupply Chain

Global Regularoty Support

GlobalRegulatory Support

1500 metric tons per year

More than one decade of
Naproxen manufacturing> 1500metric tons per year

Trusted by leading pharma comapnies

Trusted byleading pharmacompanies

Naproxen is a non-selective COX inhibitor and appears to exert anti-inflammatory action by reducing the production of inflammatory mediators like prostaglandins.

Naproxen was patented in 1967 and approved for use in the United States in 1976.

Naproxen by Dr. Reddy’s

The manufacturing of Naproxen and Naproxen Sodium has a long tradition at Dr. Reddy’s. We manufacture Naproxen for more than one decade at our cGMP site in Cuernavaca, Mexico. Today we are the 2nd largest manufacturer of Naproxen globally and reliably supply our global pharma customers with APIs and finished formulations.

Active Pharmaceutical Ingredient

  • Naproxen Base and Naproxen Na
  • Manufactured at our dedicated cGMP facility in Cuernavaca, Mexico
  • Total capacity > 1500 MT
  • Customized particle size

Finished Dosage Form

  • Naproxen Na Rx
  • Formulated at our cGMP manufacturing site in Hyderabad, India

Addressing the changing market demands in the product life cycles

Naproxen has become one of the focus products of Dr. Reddy’s and our teams are working on constant improvements an capacity expansion to meet the changing market needs. Some of our approaches include.

  • Robust supply chain – most of our key starting materials are now backward integrated and we have diversified our raw material sourcing through long term contracts and sourcing efficiencies to facilitate sustainable supplies.
  • Capacity expansion – we have been working consistently over last one year to increase our manufacturing capacity by 50%.
  • Continuous improvement – during the API life cycle, we regularly improve process efficiency and quality.
  • Product life-cycle management – on request we are able to provide new formulations such as Naproxen Na OTC
  • Facilitating formulation needs – on request we are able to supply formulators with DC grade granules of Natproxen Na to facilitate faster formulation development and manufacturing.

FAQs

What are the uses of Sugammadex Sodium API?
  • Reverses neuromuscular blockade induced by rocuronium and vecuronium during surgery.

What are the precautions to take while using Sugammadex Sodium?
  • Monitor for allergic reactions
    Avoid in patients with severe renal impairment.

How do you store Sugammadex Sodium API?
  • Store at 20°C to 25°C (68°F to 77°F), protect from moisture.

Disclaimer

No information on this website, including any reference to any product or service constitutes an offer for sale or be construed as representing an offer for sale. Products protected under valid patents are not offered or supplied for commercial use. However, in certain cases, at Dr. Reddy's sole discretion, and subject to local legal requirement, the research quantities of such products may be offered for the purpose of regulatory submissions under Section 107A of the Indian Patent Act (Bolar exemption), wherever such regulatory exemptions exist. The buyers should make their independent evaluation of the product or service including, patent scenario in their respective markets and will be responsible for all patent related liabilities Dr. Reddy's disclaims all warranties, express or implied, including but not limited to warranties of merchantability, fitness for a particular purpose and non-infringement.

Disclaimer: Products under patent(s) are offered only for R&D purposes U/S 107A of the Patent Act (Bolar Exemption) and not for commercial sale.